Brain Fire: Immune system and medical disorders in autism: current knowledge, testing & treatments
A half-day event exploring the role of the immune system and mast cells in autism, as well as evidence-based approaches on identifying comorbid and/or underlying medical conditions in individuals with autism.
The event is suitable for both and parents and professionals – health professionals will be able to claim CPD points under the latest scheme guidance by their Medical College.
‘Brain Fires in Autism: Mast Cells, Microglia and Brain Inflammation’
Dr Theoharis C. Theoharides, BA, MS, MPhil, PhD, MD, FAAAAI
Autism remains without effective treatment due to the lack of distinct pathogenesis and objective biomarkers. In addition to the typical symptoms of autism, many children have allergic problems, especially food intolerance, which involves activation of mast cells. Recent epidemiological studies have shown a strong statistical correlation between the risk for autism and either maternal or infantile atopic diseases, such as asthma, eczema, food allergies and food intolerance, all of which involve activation of mast cells. Moreover, it has been reported that the risk of autism is ten times higher than the general population in mastocytosis, a disorder characterized by increased number of hyperactive mast cells. Mast cells could contribute to focal brain inflammation and autism through different ways and their regulation could have important therapeutic benefit in autism.
About the speaker: Dr. Theoharides is Professor of Pharmacology and Internal Medicine, as well as Director of Molecular Immunopharmacology and Drug Discovery, in the Department of Integrative Physiology and Pathobiology at Tufts University School of Medicine, Boston, MA. He was born in Thessaloniki, Greece, and graduated with Honors from Anatolia College. He received all his degrees with Honors from Yale University, and was awarded the Dean’s Research Award and the Winternitz Price in Pathology. He trained in internal medicine at New England Medical Center, which awarded him the Oliver Smith Award “recognizing excellence, compassion and service.” He also received a Certificate in Global Leadership from the Tufts Fletcher School of Law and Diplomacy and a Fellowship at the Harvard Kennedy School of Government. He has been serving as the Clinical Pharmacologist of the Massachusetts Drug Formulary Commission continuously since 1986. In Greece, he has served on the SupremeAdvisory Health Councils of the Ministries of Health and of Social Welfare, as well as on the Board of Directors of the Institute of Pharmaceutical Research and Technology, and he is a member of the International Advisory Committee for the University of Cyprus School of Medicine. He is a member of 15 academies and scientific societies. He was inducted into the Alpha Omega Alpha National Medical Honor Society and the Rare Diseases Hall of Fame.
Theoharides Lab research page with a list of publications
‘Evidence-based Medical Diagnostics in Autism – How it can help your child ’
Agnieszka Wroczyńska MD PhD
Recent scientific evidence shows that many medical conditions are not only highly prevalent in individuals autism and contribute to lower quality of life, high mortality and early deaths, but can often contribute to overall severity of autism symptoms. Many of those conditions can both be ruled out and, when identified, can be treated with existing evidence-based treatments.
This talk will focus on identifying possible underlying or comorbid medical conditions in autism, such as inborn errors of metabolism, mitochondrial dysfunction, epilepsy and subclinical epileptiform discharges; gastrointestinal disorders with high prevalence in autism such as celiac disease, reflux disorders and eosinophilic esophagitis; immune dysfunction and allergies, mast cell activation disorders, autoimmune encephalitis, PANDAS/PANS and others.
The talk will cover possible symptoms: when to suspect specific conditions – their possible signs and manifestations, especially in young children or those with impaired or minimal communication skills; available tests; and overview of existing evidence-based treatments in the UK and beyond.
About the speaker: Agnieszka Wroczyńska MD PhD, Medical University of Gdansk. Dr Wroczyńska is a board certified internal medicine specialist. She works as attending physician in the Department of Tropical and Parasitic Diseases and academic teacher in a National Centre of Tropical Medicine, Medical University of Gdansk and has published over 50 articles in peer reviewed journals, conference presentations and book chapters. Since 2014 she has been the physician in charge of her 10 years old son with autism and complex medical issues.
The event will take place on Friday 1 December, from 10am-1pm.
Location: Conway Hall, 25 Red Lion Square, London WC1
Only £15 per person (free to members).
Members note: if you are a member you will still need to register and purchase a ticket via the link below. The price of your ticket will be refunded after the event).
Where can I contact the organiser with any questions?
Email us at firstname.lastname@example.org, Tel: 07510933282
Can I bring children to the event?
No. The event is aimed at parents and not appropriate for children. Unfortunately, we are unable to provide childcare facilities, nor there is space to accommodate children. We apologize for the inconvenience caused.
Is my registration/ticket transferrable?
Yes. However, if someone else is coming instead of you, please let us know by email.
Do I have to bring my printed ticket to the event?
We will have your name on the door, but please bring the ticket along, if you are able to print it at home. You can also show it to us at the door on your phone screen.
What is the refund policy?
Tickets cancelled no later than three days before the event will be refunded in full. We cannot offer refunds for tickets cancelled on or after 24 November 2017.
I am a Treating Autism member. Why am I required to purchase a ticket?
Treating Autism members need to book their ticket and confirm attendance through the standard booking procedure. We are unable to process reservations in a different way. If you are a member of Treating Autism, you will receive a full refund for your purchased ticket shortly after attending the event. Please note that refunds can only be issued to members who attend the event, or to those who cancel their booking no later than 24 November 2017.
For those who are not members of Treating Autism, there will be an opportunity to join as a member on the day, in which case a full refund will also be issued.
Can tickets be purchased at the door?
Yes, subject to availability. However, booking in advance is recommended, as we cannot guarantee that there will be spaces available at the door.
What are my transport/parking options getting to the event?
Details on the venue and how to get there can be found on venue website.
Note: We have a number of free tickets available for parents who are not members, but are unable to afford the fee. Please write to us to request a free admission.
LOCATION: Conway Hall, 25 Red Lion Square, London WC1
VENUE: Conway Hall
START DATE: December 01st, 2017
END DATE: December 01st, 2017